-IBIS-1.5.0-
rx
chemistry screen
direct bilirubin
diagnoses
definition
reference ranges:
standard: 0.0-0.3 mg/dl
healthy: 0.0-0.2 mg/dl
conditions that can exhibit an increase in direct bilirubin:
Liver disease (hepatitis); Hemolytic disease; Obstruction of biliary system.
conditions that can exhibit a decrease in direct bilirubin:
No known clinical significance.
in general: if direct bilirubin is:
< 20 % of total bilirubin: hemolysis, benign hyperbilirubinemia (Gilbert's disease)
20-40% of total bilirubin: Probably liver and not biliary obstructive disease.
40-60% of total bilirubin: either liver or post-hepatic jaundice.
>50% of total bilirubin: Post-hepatic not liver jaundice.
>40 mg/dl: Hepatocellular not extrahepatic obstruction.
footnotes