-IBIS-1.5.0-
rx
toxidrome
Cyanogenic glycoside toxidrome
botanicals
definition
cyanogenic glycoside toxidrome
the following toxicity information is largely derived from poisonings, overdoses and research on isolated constituents; used with appropriate clinical judgment and cautious prescribing, herbs are safe and efficacious
plants included:
» Hydrangea arborescens
» Prunus spp.
plants containing cyanogenic glycosides but with no reported cases of toxicity:
» Sambucus spp.
» Rosa spp.
» Trifolium arvense, pratense
» Turnera diffusa
» Hydrangea arborescens:
Cyanogenic glycoside toxidrome: abdominal pain, nausea, vomiting, vertigo, diaphoresis, and lethargy. Flaccidity, incontinence, tetany, convulsions and cyanosis may also occur. The patient may experience a feeling of oppression in the chest (AMA, pp. 94-95; der Marderosian et al, p. 118; Duke, p. 237; Woodward, pp. 17, 177)
» Prunus spp.:
Cyanogenic glycoside toxidrome: abdominal pain, nausea, vomiting, and diaphoresis. Diagnostic signs include: bitter taste in mouth, cyanosis, mydriasis, ataxia, often with falling, labored gasping respirations, rolling of the eyes, flaccidity, lassitude, and lethargy. Incontinence, tetany, and convulsions can ensue (AMA, p. 138; Woodward, p. 40; Levy and Primack, p. 90). May also produce blindness, alopecia, and a loss of mental faculties (Duke, pp. 394-395).
potentially narcotic (Duke, pp. 394-395)
footnotes
Duke, J.A. 1985. C.R.C. Handbook of Medicinal Herbs. Boca Raton, FL: The C.R.C. Press.
Lampe, K.F., and McAnn, M.A. 1985. AMA Handbook of Poisonous and Injurious Plants. Chicago: American Medical Association.
Levy, C.K.; and Primack, R.B. 1984. A Field Guide to Poisonous Plants and Mushrooms of North America. The Stephen Green Press.
Ara der Marderosian, L.L. 1988. Natural Product Medicine: a Scientific Guide to Foods, Drugs, Cosmetics. Philadelphia: George F. Stickley Co.
Woodward, L. 1985. Poisonous Plants: A Color Field Guide. New York: Hippocrene Books, Inc.