-IBIS-1.5.0-
rx
herb
Spigelia marilandica (Pinkroot)
botanicals
definition
botanical name(s): Spigelia marilandica
synonyms: pinkroot
part(s) used: root, rhizome
qualities:
affinities:
actions:
dosage:
» powder: children over 4 years: 0.3-1.3 g.; adults: 2-5 g. (Felter and Scudder, p. 651)
therapy:
AHPA Botanical Safety Rating: 2d
toxicity: 4
» overdose treatment: fluids, monitor blood volume and pH; beware of renal complications resulting from rhambdomyolysis (AMA, p. 162; Brundage, p. 215; Phillips, p. 130)
» do not exceed recommended dose; not for long-term use (McGuffin)
» spigeline causes nausea, vomiting, vertigo, mydriasis, dry throat, dimness of vision, accompanied by an increase in pulse rate, flushing, drowsiness, and hot, dry skin; there may be swelling of eyelids, with strabismus, staring, and a trembling tongue; strychnine-like convulsions can ensue, characterized by rigidity tetany, myoclonic spasms, and hyperextension reflexes with hypercontractility in the conscious state; convulsions and prostration may occur, followed by death due to depression of motor activity and cardiorespiratory problems; narcotic effects have been noted (AMA, p. 162; Brundage, p. 215; Duke, p. 456; Phillips, p. 130; Simpson and Curtis, pp. 211-218; von Oettingen, pp. 543-544)
constituents: spigeleine, an alkaloid; essential oil, tannin
footnotes
Brundage, A.H. 1929. A Manual of Toxicology, 15th ed. New York: D. Appleton and Co.
Duke, J.A. 1985. C.R.C. Handbook of Medicinal Herbs. Boca Raton, FL: The C.R.C. Press.
Felter, H.W. & Scudder, John K., 1922. The Eclectic Materia Medica, Pharmacology and Therapeutics. Cincinnati, Ohio. Reprinted in 1985 by Eclectic Medical Publications, Portland, OR.
Lampe, K.F., and McAnn, M.A. 1985. AMA Handbook of Poisonous and Injurious Plants. Chicago: American Medical Association.
McGuffin, Michael, ed. 1997. American Herbal Products Associations Botanical Safety Handbook. Boca Raton, FL: The CRC Press.
Phillips, C.D. 1879. Materia Medica and Therapeutics: Vegetable Kingdom. New York: William Wood and Company.
Simpson, L.L., Curtis, D.R. 1977. Neuropoisons; Their Pathophysiological Actions. New York: Plenum Press.
von Oettingen, W.F. 1958. Poisoning: A Guide to Clinical Diagnosis and Treatment. Philadelphia: W.B. Saunders and Company.