-IBIS-1.5.0-
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toxidrome
Sennoside toxidrome
botanicals
definition
sennoside toxidrome
the following toxicity information is largely derived from poisonings, overdoses and research on isolated constituents; used with appropriate clinical judgment and cautious prescribing, herbs are safe and efficacious
plants included:
» Cassia spp.
» Rhamnus catharticus, Rhamnus frangula, Rhamnus purshiana
overdose treatment is symptomatic with fluids and electrolytes
sennoside toxidrome: severe abdominal pain with griping and inflammation, nausea, vomiting, and a severe (often bloody) diarrhea; often accompanied by dry mouth and severe thirst from fluid loss
habituation and chronic use result in weakness, hypokalemia, and melanization of the colon; serious cases involve children and slender individuals (Duke, p. 403; Levy and Primack, p. 117)
laboratory test results: dark urine is indicative of use or abuse of this plant
footnotes
Duke, J.A. 1985. C.R.C. Handbook of Medicinal Herbs. Boca Raton, FL: The C.R.C. Press.
Levy, C.K.; and Primack, R.B. 1984. A Field Guide to Poisonous Plants and Mushrooms of North America. The Stephen Green Press.