-IBIS-1.7.6-
tx
mental/emotional
anxiety
Botanicals
primary herbs
Anemone pulsatilla (toxic): insomnia, with Passiflora incarnata (British Herbal Pharmacopoeia, p. 174)
Betonica officinalis (British Herbal Pharmacopoeia, p. 42)
Brassica spp. (mustard): as foot bath: one handful of mustard powder to 2-3 gallons of water, no longer than 10 min. (Husemann, p. 389)
Bryonia alba (toxic)
Chamomilla: Chamamaelum nobilis, Matricaria chamomilla
Humulus lupulus (strobiles): nervous excitability, induces sleep (Felter, p. 407)
Hyssopus officinalis (British Herbal Pharmacopoeia, p. 116)
Passiflora incarnata: irritation, insomnia from worry, overwork (Felter, p. 515)
Piper methysticum (Felter, p. 546)
Primula veris: anxiety states associated with restlessness and irritability, with Scutellaria lateriflora (British Herbal Pharmacopoeia, p. 171)
Scutellaria lateriflora: nervous tension states; combines well with Humulus lupulus and/or Passiflora incarnata (British Herbal Pharmacopoeia, p. 194)
Selenicereus grandiflorus (toxic): anxiety associated with heart conditions (Felter, p. 253)
Tilia platyphyllos: sedative; combines with Humulus lupulus (British Herbal Pharmacopoeia, p. 214)
Turnera diffusa: anxiety neurosis with predominant sexual factor (British Herbal Pharmacopoeia, p. 220)
Valeriana spp.: anxiety with fear; nervousness, depression (Felter, p. 685)
complementary herbs
Valeriana spp. + Chamomilla spp. + Humulus lupulus + Scutellaria lateriflora (NCNM Botanicals)
Valeriana spp. + Passiflora incarnata + Scutellaria lateriflora + Lobelia inflata (toxic); may add Humulus lupulus (Turska)
Euphytose: Crataegus, Ballota, Passiflora, Valeriana, Cola and Paullinia.
(Bourin M, et al. Fundam Clin Pharmacol 1997;11(2):127-132.)
footnotes
Almeida JC, Grimsley EW. Coma from the health food store: Interaction between kava and alprazolam. Arch Intern Med 1996;125:940-941.
Baureithel KH, Buter KB, Engesser A, et al. Inhibition of benzodiazepine binding in vitro by amentoflavone, a constituent of various species of Hypericum. Pharm Acta Helv 1997;72:153-157.
Bourin M, Bougerol T, Guitton B, Broutin E. A combination of plant extracts in the treatment of outpatients with adjustment disorder with anxious mood: controlled study versus placebo. Fundam Clin Pharmacol 1997;11(2):127-132.
Abstract: Euphytose (EUP) is a combination of six extracts: Crataegus, Ballota, Passiflora and Valeriana, which have mild sedative effects, and Cola and Paullinia, which mainly act as mild stimulants. This multicenter, double-blind, placebo-controlled general practice study was carried outpatients with adjustment disorder with anxious mood. The study was coordinated by psychiatrists. Ninety-one patients were included in the EUP group and 91 patients in the placebo group. They all received two tablets three times a day over 28 days (D). Evaluation using the Hamilton-anxiety (HAM-A) rating scale were carried out on D0, D7, D14 and on D28. Comparing the two groups, 42.9% of the patients (EUP group) had a HAM-A score of less than 10 at D28 versus 25.3% in the placebo group (P = 0.012). Changes in the HAM-A score between D0 and D28 were as follows: D0 (EUP: 26.12 +/- 4.0, placebo: 26.27 +/- 4.5), D7 (EUP: 19.65 +/- 5.7, placebo: 21.37 +/- 5.6), D14 (EUP: 15.36 +/- 5.7, placebo: 17.48 +/- 6.7), D28 (EUP: 12.63 +/- 7.3, placebo: 15.2 +/- 8.1). From D7 to D28 there was a statistically significant difference (P = 0.042) between the two treatments, indicating that EUP is better than placebo in the treatment of adjustment disorder with anxious mood.
British Herbal Medicine Association. British Herbal Pharmacopeia. West Yorks, England: BHMA, 1983.
Brown D. Valerian root: Non-addictive alternative for insomnia and anxiety. Quart Rev Nat Med 1994; Fall:221-224. (Review)
Lehmann EE, Kinzler J, Friedmann J. Efficacy of a special kava extract (Piper methysticum) in patients with states of anxiety, tension and excitedness of non-mental origin. A double-blind placebo-controlled study of four weeks treatment. Phytomedicine 1996;3:113-119.
Piscopo G. Kava kava: Gift of the islands. Alt Med Rev 1997;2:355-381. (Review)
Viola H, de Stein ML, et al. Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects. Planta Med 1995;61:213-216.
Volz HP, Kieser M. Kava-kava extract WS 1490 vs. placebo in anxiety disorders - A randomized placebo-controlled 25-week outpatient trial. Pharmacopsychiatry 1997;30:1-5.
Warnecke G. Psychosomatic dysfunctions in the female climacteric. Clinical effectiveness and tolerance of kava extract WS 1490. Fortscher Med 1991;119-122. [Article in German]
Witte B, Harrer G, Kaptan T, et al. Treatment of depressive symptoms with a high concentration Hypericum preparation. A multicenter placebo-controlled double-blind study. Fortschr Med 1995;113:404-408. [Article in German]
Woelk H, Kapoula S, Lehrl S, et al. Treatment of patients suffering from anxiety - double-blind study: Kava special extract versus benzodiazepines. Z Allegemeinmed 1993;69:271-277. [Article in German]
Yamada K, Miura T, Mimaki Y, Sashida Y. Effect of inhalation of chamomile oil vapour on plasma ACTH level in ovariectomized rats under restriction stress. Biol Pharm Bull 1996;19:1244-1246.