-IBIS-1.5.0-
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nervous system
Down's syndrome
nutrition
dietary guidelines
Dietary: avoid allergens and consider following ABO blood typing recommendations (Marz; DAdamo)
supplements
multivitamin-mineral plus thyroid (Harrel; Austin)
Selenium 200-400 mcg per day
Adrenal function enhancement: The adrenal glands are considered essential for proper immune function, they are particularly involved with the prevention of aging and they have been used to treat chronic fatigue
Piracetam: acts to increase neurotransmitters in the brain; also acts as an antioxidant. Studies have used 7.2 g up to 20 per day (Marz, p. 478, 1997)
Cardiovascular disease
Antioxidant nutrients
Coenzyme Q 10
Taurine
Carnitine
Brain function
Phosphatidyl choline: is a precursor to acetylcholine, a vital brain neurotransmitter. May be used in conjunction with other Nootropic drugs such as Piracetam.
Tyrosine: is a precursor to epinephrine and norepinephrine which are important neurotransmitters. In addition, it is a precursor to thyroid hormones.
Tryptophan: is especially useful for calming the brain to enhance concentration and also to improve sleeping.
Ginkgo biloba: has had a long history of improving cognitive brain function as well as memory. In addition it has marked effects on improving circulation and also acting as an antioxidant in various tissues.
Thyroid: consider zinc, copper, tyrosine and thyroid glandulars or straight T4.
Carnitine: The L-acetylcarnitine form may significantly improve the symptoms of depression and memory problems. L-acetylcarnitine is a major neurotransmitter in the brain. There have been numerous studies to date which have shown benefits in mental function, particularly in enhancing memory and constructional thinking. Because Down Syndrome shares many of the characteristic brain abnormalities that Alzheimers disease does and its efficacy hs been studied. There have been some favorable studies using L-acetylcarnitine.
(Cipolli, C., Chiari, G Clin Ther 132, 479-510, 1990).
footnotes
Cipolli, C., and Chiari, G. Effects of L-acetylcarnitine on mental deterioration in the aged: Initial results Clin Ther 132, 479-510, 1990
Abstract: 236 elderly patients with mild mental deterioration in a double blinded clinical trial who received 1500mg L-acetylcarnitine per day showed significant improvement in memory and other mental functions.