-IBIS-1.5.0-
tx
endocrine system
diabetes mellitus
chinese formulae
formulas
Ning Xue Tang: diabetic retinopathy (Bensky and Barolet, p. 338)
Si Miao Yong An Tang plus salvia (dan shen), red peony (chi shao yao) and moutan bark (mu dan pi): Fire Toxin, Xue Yu (Blood Stasis): diabetic skin ulcerations
(Yeung, p. 215; Bensky and Barolet, p. 85)
» Upper Warmer: excessive thirst predominant
Ginseng and Gypsum C. (Bai Hu Jia Shen Tang): Lung Yin Xu (Deficiency)
(Hsu, 1980, p. 183; Yeung, p. 37; Bensky and Barolet, p. 71)
» Middle Warmer: excessive hunger predominant
Rehmannia and Gypsum C. (Yu Nu Jian): Stomach Yin Xu (Deficiency)
(Hsu, 1980, p. 201; Yeung, p. 279; Bensky and Barolet, p. 94)
Ophiopogon and Rehmannia C.: Kidney Yin Xu (Deficiency) with weak digestive function
(Terashi, p. 126)
» Lower Warmer: excessive urination predominant
Phellodendron C.; Yu Chuan Wan (patent): Kidney Yin Xu (Deficiency) with Empty Fire Blazing
(Phellodendron: Hsu, 1980, p. 199; Dharmananda, 1986, p. 174; Yu Chuan Wan: Zhu, p. 309)
Rehmannia Eight F. (Jin Gui Shen Qi Wan): Kidney Yin Xu (Deficiency) with Kidney Yang Xu (Deficiency): Early-onset (insulin-dependent) diabetes
(Hsu, 1980, p. 250; Yeung, p. 138; Dharmananda, 1986, p. 173; Bensky and Barolet, p. 275)
Rehmannia Six F. (Liu Wei Di Huang Wan) (available as patent); Rehmannia 16 (patent); Cuscuta 15 (patent): Kidney Yin Xu (Deficiency)
(Rehmannia 6: Hsu, 1980, p. 245; Yeung, p. 152; Dharmananda, 1986, p. 172; Bensky and Barolet, p. 263; Rehmannia 16: Dharmananda, 1990, p. 23; Cuscuta 15: Dharmananda, 1990, p. 15)
Quan Lu Wan (patent): Adult diabetes with both Kidney Yin Xu (Deficiency) and Kidney Yang Xu (Deficiency) (Zhu, p. 307)
Ci Wu Jia Pian (patent): tonic to increase gland function (Zhu, p. 284)
footnotes
Vray M, Attali JR. Randomized study of glibenclamide versus traditional Chinese treatment in type 2 diabetic patients. Chinese-French Scientific Committee for the Study of Diabetes. Diabete Metab 1995 Dec;21(6):433-439.
Abstract: The purpose of this study was to evaluate the efficacy of a traditional Chinese treatment (TCT) based on three plants in association with a sulfonylurea, glibenclamide (2.5 mg X 3/d). A 2 X 2 factorial design was adopted for this multicentre randomized double-blind trial involving 4 groups [A = placebo (P) TCT + P glibenclamide; B = P TCT + verum glibenclamide; C = verum TCT + P glibenclamide; D = verum TCT + verum glibenclamide]. Patients included were type 2 diabetic outpatients, 40-70 years of age, treated by diet alone or oral anti-diabetic drugs. Endpoint criteria evaluated were HbA1, blood glucose and plasma insulin (at fasting, and 1 and 2 h after a test meal). At each visit, a clinical examination was performed, and a questionnaire on side effects and associated symptoms was completed. The dose was reduced by half in the case of hypoglycaemia. The 216 patients were recruited in 5 centres [Shanghai (1) = 48, Shanghai (2) = 40, Beijing = 40, Canton = 42, Chengdu = 46 and randomized into treatment groups A, B, C, D (56, 56, 50 and 54 respectively). Eleven patients were withdrawn for administrative reasons. In patients treated with glibenclamide, a significant increase in weight and insulinaemia was observed, together with a significant decrease in blood glucose values; in those receiving TCT, blood glucose values were significantly decreased only 2 h after the test meal. A synergistic effect on blood glucose was observed when both treatments were given. Hypoglycaemia occurred in 19 patients (all in the two verum glibenclamide groups). This first multicentre controlled trial showed that the 3 Chinese plants tested were well-tolerated and effective in Type 2 diabetes as indicated by a significant synergistic effect in association with a sulfonylurea.